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Fig. 5 | Parasites & Vectors

Fig. 5

From: Stimulation of IL-1β and IL-6 through NF-κB and sonic hedgehog-dependent pathways in mouse astrocytes by excretory/secretory products of fifth-stage larval Angiostrongylus cantonensis

Fig. 5

The expressions of IL-1β and IL-6 were increased through the Shh in ESP treatment. Western blot analysis of IL-1β and IL-6 in astrocytes co-cultured with ESP alone or pretreated with Shh siRNA for 48 h and then with a recombinant Sonic hedgehog peptide from mouse (Shh) (3 μg) for 2 h and 500 μg/ml ESP for 4 h. Data are expressed as the mean ± SD from three independent experiments (*P < 0.05, **P < 0.01, ***P < 0.001)

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