Fig. 4From: Functional characterization of two defensins, HlDFS1 and HlDFS2, from the hard tick Haemaphysalis longicornis HlDFS1 and HlDFS2 significantly protect mice against lethal infection of S. aureus and M. luteus. Mice were infected with lethal doses of M. luteus (a) (1 × 106 cfu per C3H/HeJ mouse) and S. aureus (b) (1 × 108 cfu per C57/BL6 mouse) by i.p. injection. Six hours after infection, mice were treated by i.p. injection of HlDFS1 (100 μg/mouse), HlDFS2 (100 μg/mouse) or saline as controls. Mice were monitored daily for survival and symptoms of disease. Log-rank (Mantel-Cox) tests were used for these survival dataBack to article page