Table 2 Study design for nine studies using nine different isolates of D. immitis used to assess the efficacy of 3 μg/kg of oral moxidectin in dogs
Study | No. of dogs/Gpa | D. immitis isolate | Treatmentb | Dosage (μg/kg) | Day of inoculation | Days of treatment (oral) | Day of necropsy (PI) |
|---|---|---|---|---|---|---|---|
1 | 8 | Michigan | Moxidectin | 3 | −30 | 0 | 116 (146) |
2 | 8 | MP3 | Moxidectin | 3 | −30 | 0 | 120 (150) |
3 | 6 | ZoeKY | Moxidectin | 3 | −30 | 0 | 117 (147) |
4 | 3 | GCFL | Moxidectin | 3 | −28 | 0 | 120 (148) |
5 | 6 | ZoeAL | Moxidectin | 3 | −28 | 0 | 120 (148) |
6 | 8 | JYD-34 | Moxidectin | 3 | −30 | 0 | 122 (152) |
6 | 8 | JYD-34 | Moxidectin | 3 | −30 | 0, 30 and 60 | 122 (152) |
7 | 6 | ZoeMO | Moxidectin | 3 | −30 | 0 | 117 (147) |
8 | 6 | ZoeLA | Moxidectin | 3 | −30 | 0 | 118 (148) |
9 | 3 | AMAL | Moxidectin | 3 | −28 | 0 | 120 (148) |