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Table 1 Blood microfilaremia associated with experimental infections with two suspected ML-resistant isolates of D. immitis

From: Does evaluation of in vitro microfilarial motility reflect the resistance status of Dirofilaria immitis isolates to macrocyclic lactones?

Yazoo-2013.1

Metairie-2014

Day post infection

Dog

MF/mL

Days post infection

MF/mL

212

Dog 1

1

183

0

Dog 2

11

246

Dog 1

75

215

50

Dog 2

350

286

Dog 1

550

245

1275

Dog 2

975

320

Dog 1

2400

280

9325

Dog 2

4500

348

Dog 1

2950

323

14,325

Dog 2

5925

381

Dog 1

2825

416

32,175

Dog 2

3675

411

Dog 1

3675

665

62,400

Dog 2

3675

446

Dog 1

2550

721

75,500

Dog 2

4000

   

847

54,275

  1. Only one dog was used in the isolation of Metairie-2014. Heartgard Plus was administered to the dogs at 30, 60, 90, 120, 150 and 180 days post infection