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Table 2 Comparison of antigen detection with or without ICD using samples from necropsy-confirmed positive dogs and client-owned dogs

From: Validation of immune complex dissociation methods for use with heartworm antigen tests

Dog population

Number of positive results

No ICD treatment

ICD treatment

Heat + EDTA

Pepsin

Acidic pH

Heat

Necropsy-confirmed positive (1–2 female worms); n = 5

3

5

5

5

5

Necropsy-confirmed positive (1–11 female worms); n = 30

17

29

ND

ND

ND

Client-owned (samples submitted to reference lab); n = 181

0

4

ND

ND

ND

  1. ICD immune complex dissociation, ND not done