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Table 4 Results of flea infestations at 12 h post-treatment and 12 h after weekly infestations in Study 3

From: Assessment of the speed of flea kill of lotilaner (Credelio™) throughout the month following oral administration to dogs

 

Day of infestation and flea count

0

7

14

21

28

35

Control

Arithmetic mean ± SD

75.0 ± 7.0

71.9 ± 9.2

76.9 ± 12.8

78.0 ± 9.4

75.1 ± 6.2

82.0 ± 10.3

Geometric mean

74.7

71.4

75.9

77.6

74.9

81.4

Lotilaner

Arithmetic mean ± SD

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

Efficacy (%)

100

100

100

100

100

100

Geometric mean

0.0

0.0

0.0

0.0

0.0

0.0

Efficacy (%)

100

100

100

100

100

100

Comparison

t (5) = 78.5, P < 0.0001

t (5) = 92.6, P < 0.0001

t (5) = 42.2, P < 0.0001

t (5) = 112.6, P < 0.0001

t (5) = 146.6, P < 0.0001

t (5) = 99.0, P < 0.0001

  1. Abbreviation: SD standard deviation