Skip to main content

Advertisement

Table 2 Geometric (arithmetic) mean counts of live Dermacentor reticulatus and percent efficacy

From: Two randomized, controlled studies to assess the efficacy and safety of lotilaner (Credelio™) in preventing Dermacentor reticulatus transmission of Babesia canis to dogs

Day Untreated control Lotilaner Comparison 
Mean Range Mean Range Efficacy (%)  
Study 1
 4 22.2 (22.4) 18–29 0.2 (0.3) 0–1 99.1 (98.7) t (14) = 24.07, P < 0.0001
 9 37.6 (39.1) 23–52 0.2 (0.3) 0–2 99.5 (99.2) t (14) = 20.16, P < 0.0001
 16 13.3 (14.3) 5–19 0.0 (0.0) 0–0 100 (100) t (14) = 18.54, P < 0.0001
 23 25.1 (32.5) 4–87 0.0 (0.0) 0–0 100 (100) t (14) = 11.26, P < 0.0001
 30 23.4 (25.1) 12–41 0.0 (0.0) 0–0 100 (100) t (14) = 21.71, P < 0.0001
Study 2
 34 23.7 (24.5) 15–36 0.0 (0.0) 0–0 100 (100) t (10) = 28.45, P < 0.0001