A randomised, blinded, controlled field study to assess the efficacy and safety of lotilaner tablets (Credelio™) in controlling fleas in client-owned dogs in European countries

Table 4 Percent flea count reduction from baseline for each treatment group

	Effectiveness based on	Lotilaner	Fipronil	t-value	P-value
Day 14	Arithmetic mean	99.0	77.3
Day 14	Geometric mean	99.1	93.4	t ₍₁₈₇₎ = 4.61	P < 0.0001
Day 28	Arithmetic mean	99.3	58.0
Day 28	Geometric mean	99.5	91.2	t ₍₁₈₇₎ = 5.33	P < 0.0001
Day 56	Arithmetic mean	99.9	79.9
Day 56	Geometric mean	99.9	94.4	t ₍₁₈₇₎ = 5.01	P < 0.0001
Day 84	Arithmetic mean	99.7	88.4
Day 84	Geometric mean	99.8	97.0	t ₍₁₈₆₎ = 3.43	P = 0.0007
Overall	Arithmetic mean	99.5	75.9
Overall	Geometric mean	99.6	94.1	t ₍₁₈₇₎ = 5.69	P < 0.0001

ISSN: 1756-3305