Table 2 Description of necropsy findings in the non-dermal tissue of the Iberian ibex affected by severe sarcoptic mange
Organs | n | Gross pathologic examination | Microscopical findings |
|---|---|---|---|
Superficial LN | 206 | Lymphadenomegaly (two and three times the normal size). | Lymphoid hyperplasia with activation of LF, formation of germinal centers and increase in lympho-plasma cells and macrophages in cords and medullary sinuses (Serous lymphadenitis) (+++) |
Purulent lesion (7.76%) (Fig. 3) | Purulent lymphadenitis (7.76%) (+++) | ||
Edema | Congestion and edema (+++) | ||
Congestion | Subcapsular, follicular and medullary amyloidosis (71.35%) (++) | ||
Deep LN | 105 | Lymphadenomegaly (less than twice the normal size) | Histological pattern similar to superficial LN (++) |
Edema | Subcapsular, follicular and medullary amyloidosis (75.23%) (++) | ||
Congestion | Sarcocystis spp. (mesenteric LN) (12.38%) (+) | ||
CNS | 12 | Subdural congestion | Gliosis and perivascular cuffs of mononuclear cell (25.00%) (+) |
Tongue | 34 | None | Sarcocystis spp. with cellular infiltration (lymphocytes, mast cells and eosinophils) (58.82%) (+) |
Thyroid gland | 34 | None | None |
Skeletal muscle | 34 | None | Sarcocystis spp. with monocuclear infiltration (32.35%) (+) |
Mononuclear myositis in the absence of parasites (14.74%) (+) | |||
Heart | 34 | Hydropericardium (82.35%) | Sarcocystis spp. (44.11%) (+) |
Absence of pericardial fat | Mononuclear myocarditis (monocytes, lymphocytes and plasma cells) with infiltration of adipose cells (23.52%) (+) | ||
Chicken fat clot (35.29%) | Muscle mineralization (5.88%) (+) | ||
Lungs | 102 | Interstitial emphysema in apical lobes (41.17%) | Granulomatous inflammation with presence of intra- alveolar parasites and infiltration of eosinophils, neutrophils and lymphocytes (verminous pneumonia) (88.23%) (+++) |
Fibrotic nodular lesions in caudal lobes (88.23%) | Infiltration of neutrophils, eosinophils, macrophages and lymphocytes, congestion, edema and areas of necrosis (bacterial pneumonia) (8.82%) (+++) | ||
Infiltration of neutrophils, eosinophils, macrophages and lymphocytes, congestion, edema and areas of necrosis (bacterial pneumonia) (8.82%) (+++) | |||
Abdominal cavity | 34 | Ascitic fluid (transudate) | |
Hepatoperitoneal cysticercosis | |||
Liver | 34 | Congestion | Perivascular amyloid deposits in portal triad and hepatic sinusoids (11.76%) (++) |
Increased size | Congestion (+++) and leukocytosis (67.64%) (++) | ||
Fibrosis (8.82%) | Parasitic fibrosis (8.82%) (+) | ||
Kidney | 68 | Absence of perirenal fat | Amyloid deposits in glomerular mesangium (amyloid nephrosis) and cortical and medullary tubular interstitium with decreased capillary lumen (chronic interstitial nephritis and ischemic tubular atrophy) (20.58%) (++) |
Congestion | Mesangial thickening, tubular mineralization and leukocytosis (50.00%) (+) | ||
Adrenal gland | 68 | Increased size | Amyloid deposits in cortex and adrenal medulla (26.47%) (++) |
Increased color | Leukocytosis (5.88%) (+) and adrenal cortical hypoplasia (17.64%) (+++) | ||
Spleen | 34 | Increased size | Hyperplasia of LF with formation of germinal centers (+++) |
Lymphoid hyperplasia | Amyloid deposits in LF and PLS of the white pulp and the splenic cords and venous sinuses of the red pulp “sago spleen” (70.58%) (+++) | ||
Congestion | Congestion (+++) and leukocytosis (+) | ||
Pancreas | 26 | None | Amyloid deposits in exocrine pancreas (15.38%) (+) and leukocytosis (+) |
Intestine | 66 | Congestion | Chronic parasitic enteritis (21.21%) (++) Amyloid deposits in MALT (25.75%) (+) |
Testicle | 7 | None | None |
Ovary | 32 | None | None |