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Table 2 The effect of community mass treatment with azithromycin on the prevalence of active trachoma and ocular C. trachomatis infection

From: The impact of a single round of community mass treatment with azithromycin on disease severity and ocular Chlamydia trachomatis load in treatment-naïve trachoma-endemic island communities in West Africa

Clinical category

Prevalence (%) (95% CIa)

Prevalence (%) (95% CIa)

 

Baseline

n

Follow-up

n

TF1–9 b

22.0 (18.9–25.5)

136/618

7.4 (4.8–9.9)*

29/394

TI1–9

2.9 (1.4–4.1)

18/618

1.5 (0.3–2.7)

6/394

Ct all c

18.6 (16.7–28.8)

280/1502

3.3 (2.2–4.4)**

34/1029

Ct 1–9

25.4 (22.0–28.8)

157/618

6.6 (4.1–9.0)***

26/395

  1. aCI, confidence interval
  2. bTF1–9, TF (Trachoma-Follicular) in 1–9 year olds; TI1–9 = TI (Trachoma-Intense Inflammatory) in 1–9 year olds
  3. c Ct, C. trachomatis infection in the population overall and in 1–9 year olds 293 households were included at baseline and 254 at follow-up. Of the households lost to follow-up, 18 had C. trachomatis detected in children aged 1–9 years within the household at baseline. C. trachomatis infection status of the household at baseline was adjusted for in the follow-up analysis
  4. *P < 0.0001; Chi-square test, χ 2 = 37.5, df = 1, difference 14.6% (95% CI: 10.2–18.8%)
  5. **P < 0.0001; Chi-square test, χ 2 = 131.7, df = 1, difference 15.3% (95% CI: 13.0–17.6%)
  6. ***P < 0.0001; Chi-square test, χ 2 = 57.5, df = 1, difference 18.8% (95% CI: 14.3–23.1%))