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Fig. 2 | Parasites & Vectors

Fig. 2

From: P2X7 receptor mediates NLRP3-dependent IL-1β secretion and parasite proliferation in Toxoplasma gondii-infected human small intestinal epithelial cells

Fig. 2

Toxoplasma gondii significantly increased NLRP3 expression levels in a time-dependent manner. FHs Int 74 cells were mock-infected or infected with the T. gondii GFP-RH strain at an MOI of 10. Cells were harvested 4 or 8 h post-infection. a NLRP1, NLRP3, NLRC4 and AIM2 expression levels were determined by qRT-PCR. HPRT1 served as an internal control. *P < 0.05 compared with the mock-infection control. b NLRP1, NLRP3, NLRC4 and AIM2 protein levels in cell extracts were determined by Western blotting. All data are representative of three independent experiments

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Parasites & Vectors

ISSN: 1756-3305

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