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Fig. 6 | Parasites & Vectors

Fig. 6

From: Enhanced expressions of neurodegeneration-associated factors, UPS impairment, and excess Aβ accumulation in the hippocampus of mice with persistent cerebral toxocariasis

Fig. 6

Levels of substance P (SP), the interleukin (IL)-1β precursor and IL-1β, which were also correlated with the neuroinflammatory response, were higher in the hippocampus of Toxocara canis-infected mice inoculated with low-, medium- and high-dose infections at 8, 16 and 20 weeks post-infection (wpi). a Protein accumulation in the mouse hippocampus was analyzed by Western blotting. b-d Quantification of SP, the IL-1β precursor, and IL-1β accumulation in the hippocampal region. Data are presented as the mean with SD. *P < 0.05, **P < 0.01 and ***P < 0.001 indicate a significant difference with uninfected control mice at 10 days post-infection (dpi) and 20 wpi. Abbreviation: NS, no significant difference between 10 dpi- and 20 wpi-uninfected control mice

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Parasites & Vectors

ISSN: 1756-3305

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