Fig. 3

Characterization of the clonality of an infection. The variations in the proportion of single or multiple clone infections (a) and the geometric mean MOI in Abura and Obom over the study period (b). After PCR amplification of either msp2 or glurp from gDNA extracted from dried blood spots of the children, the children were grouped into categories depending on the total number of infecting parasite clones that were contained in each asymptomatic infection. The presence of either a single msp2 or glurp allele (clonal), or multiple alleles (a) was documented. The geometric mean MOI for all the asymptomatic children from Obom and Abura was determined for each month (b). The 95% confidence intervals of the GM are represented as the error bars in (b)