Table 5 Comparison of NECT cure rates in clinical trials and case series conducted to date
Reference | Test of cure | NECT | Eflornithine | Difference | |||||
|---|---|---|---|---|---|---|---|---|---|
n | % | 95% CI | n | % | 95% CI | % | 95% CI | ||
Priotto et al. [15] | Treated | 52 | – | – | 51 | – | – | – | – |
Cure | 47 | 90.4 | 80.5–100.3 | 46 | 90.2 | 80.1–100.3 | 0.2 | -9.4–9.8 | |
Priotto et al. [12] | Treated | 143 | – | – | 143 | – | – | – | – |
Cure | 129 | 90.2 | 84.7–95.8 | 123 | 86.0 | 79.6–92.4 | 4.2 | -2.1–10.5 | |
Cure or probable cure | 138 | 96.5 | 92.8–100.2 | 131 | 91.6 | 86.4–96.8 | 4.9 | 0.3–9.5 | |
This study | Treated | 55 | – | – | 54 | – | – | – | – |
Cure | 50 | 90.9 | 81.5–100.3 | 48 | 88.9 | 78.7–99.1 | 2.0 | -7.5–11.5 | |
Priotto et al. [11] | Treated | 31 | – | – | – | – | – | – | – |
Cure | 29 | 93.5 | 81.7–105.4 | – | – | – | – | – | |
Checchi et al. [24] | Treated | 17 | – | – | – | – | |||
Cure | 16 | 94.1 | 77.2–111.1 | – | – | – | – | ||