Table 2 Reported performance characteristics of selected commercial heartworm antigen tests used in dogs
Test | % Sensitivity (number of live adult female heartworms) | % Specificity | Heartworm positive/total tested | Reference |
|---|---|---|---|---|
DiroCHEK® | 85.7 (1), 95 (2), 100 (≥ 3) | 100 | 108/208b, c, d, e | [1] |
PetChek® HTWM PF | 76.2 (1), 85 (2), 100 (≥ 3) | 100 | ||
Solo Step® CHBatch | 71.4 (1), 95 (2), 96.5 (≥ 3) | 100 | ||
Solo Step® CH | 76.2 (1), 95 (2), 96.5 (≥ 3) | 100 | ||
ICT Gold® HW | 61.9 (1), 85 (2), 93 (≥ 3) | 100 | ||
SNAP® Heartworm PF | 76.2 (1), 85 (2), 100 (≥ 3) | 100 | ||
Witness® HW | 71.4 (1), 90 (2), 94.7 (≥ 3) | 100 | ||
AbboScreen™ | 71.4 (1), 100 (2), 93 (≥ 3) | 96 | ||
FILARIA IC (Italian) | 76.2 (1), 85 (2), 100 (≥ 3) | 100 | ||
Witness™ HW (Australian) | 66.7 (1), 90 (2), 94.7 (≥ 3) | 100 | ||
VetScan CHAT | 78 | 97 | 208/240b, e | [2] |
SNAP® Heartworm RT | 84 | 97 | ||
Solo Step® CH | 79 | 97 | ||
PetChek® HTWM PF | 45 (0a), 77 (1–2), 94 (≥ 3) | 97 | 140/237e | [10] |
DiroCHEK® | 40 (0a), 71 (1–2), 94 (≥ 3) | 94 | ||
SNAP® Heartworm PF | 35 (0a), 65 (1–2), 94 (≥ 3) | 98 | ||
Solo Step® CH | 35 (0a), 56 (1–2), 90 (≥ 3) | 98 | ||
AbboScreen | 30 (0a), 46 (1–2), 84 (≥ 3) | 96 | ||
VetScan VS2 | 33 | 100 | 40/90e | [11] |
SNAP® Heartworm RT | 90 | 100 | ||
SNAP® Heartworm RT | 90.9 | 98.8 | 84/150b, f | [37] |
Witness® Heartworm | 97.0 | 96.4 | ||
Filarchek | 97.6 | 100 | 41/107 | [60] |
VetScan | 92 | 100 | 25/49e | [61] |
DiroCHEK® | 100 (≥3) | 100 | NR | [62] |
Witness® Heartworm | 97.7 | 99.3 | 134/285e, f | [63] |