Prime detection of Dirofilaria immitis: understanding the influence of blocked antigen on heartworm test performance

Table 3 Reported performance characteristics of selected commercial heartworm antigen tests used in cats

Test	% Sensitivity	% Specificity	Heartworm positive/total tested	Reference
VetScan	79.9	99.7	29/380^a	[61]
DiroCHEK®	89.7	100	39/81^{a, b, c, d}	[64]
SNAP® Feline Triple®	89.3	99.5	26/238^{a, e}	[65]
DiroCHEK®	78.9	98.1	19/330^{a, b}	[66]
SNAP® Feline HTWM	73.7	99.4	19/330^{a, b}	[66]
SNAP® Feline HTWM	79.3	98.0	29/380^{a, b}	[67]
CHAT Canine HTWM	79.3	99.7
DiroCHEK®	86.2	99.1

^aInfection verified by necropsy
^bHeartworm infection established naturally
^cHeartworm infection established by subcutaneous injection of third-stage larvae
^dHeartworm infection established by surgical transplantation
^eInfection verified by comparison to PetChek® HTWM PF

ISSN: 1756-3305