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Fig. 7 | Parasites & Vectors

Fig. 7

From: Prevalence of Plasmodium falciparum delayed clearance associated polymorphisms in adaptor protein complex 2 mu subunit (pfap2mu) and ubiquitin specific protease 1 (pfubp1) genes in Ghanaian isolates

Fig. 7

A sequence alignment of pfubp1 gene showing amino acid changes due to single nucleotide polymorphisms. The alignment was done using pfubp1 reference sequence of the 3D7 strain (PF3D7_0104300). Mutations from codons 1483–1549 at nucleotide positions 4449–4647 is shown. The gaps are a result of the insertions of amino acids which resulted in a frameshift. The gap between 1519E and 1520K are therefore a result of a 6 amino acid insertion in C356, G001 and G025. The known mutations D1525E and E1528D are shown in the isolates N061 and N096 respectively. A frameshift mutation is observed in N084, after codon 1536 as a result of a deletion

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