Table 1 Summary of replicative stages in the P. falciparum life-cycle
From: Checks and balances? DNA replication and the cell cycle in Plasmodium
Replicative stage | Host | Time period | Daughter cells | Rounds of replication | Time available per genome replication | Key references |
|---|---|---|---|---|---|---|
Hepatic schizogony | Human (liver) | ~ 7 days | > 10,000 | ~ 14 | ~ 12 h | |
Erythrocytic schizogony | Human (bloodstream) | 48 h | ~ 16–20 | 4–5 | ~ 4 h | [13] |
Gametogenesis | Mosquito | 15 min | 8 | 3 | < 4 min | |
Sporogony | Mosquito | ~ 10 days | ~ 10,000 | ~ 14 | ~ 17 h |