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Fig. 3 | Parasites & Vectors

Fig. 3

From: The Toxoplasma gondii ME-49 strain upregulates levels of A20 that inhibit NF-κB activation and promotes apoptosis in human leukaemia T-cell lines

Fig. 3

Effects of T. gondii ME-49 on A20, pNF-κB p65, NF-κB p65, ABIN1, Cleaved-Casp8 (p43/p41) expression levels and the apoptosis effects induced by T. gondii ME-49 after A20 knockdown. a, b Western blot analysis of knockdown efficiency of lentivirus in Jurkat T-cells and Molt-4 T-cells. c, d The apoptosis rate in Jurkat T-cells and Molt-4 T-cells infected with T. gondii ME-49 (5 × 106 cells/ml) after A20 knockdown. e, f The A20, pNF-κB p65, NF-κB p65, ABIN1, Cleaved-Casp8 (p43/p41) protein levels in Jurkat T-cells and Molt-4 T-cells infected with T. gondii ME-49 (5 × 106 cells/ml) after A20 knockdown. Values are presented as the mean ± SD (n = 3). *P < 0.05 vs the control group; **P < 0.01 vs the control group; #P < 0.05 vs the ME-49 group

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Parasites & Vectors

ISSN: 1756-3305

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