|
Concentration (mg/ml)
|
C. aurantifolia
|
A. nobilis
|
L. officinalis
|
|---|
|
3.0
|
–
|
100.0 ± 0.0a,b
|
95.3 ± 1.84a,b
|
|
1.5
|
100.0 ± 0.0a,b
|
100.0 ± 0.0a,b
|
89.8 ± 0.88b
|
|
0.75
|
100.0 ± 0.0a,b
|
97.2 ± 2.26a,b
|
81.4 ± 1.83b
|
|
0.375
|
90.1 ± 1.68b
|
86.4 ± 2.34b
|
64.2 ± 1.79b
|
|
0.187
|
85.4 ± 2.62b
|
67.1 ± 3.26b
|
35.9 ± 0.98b
|
|
0.0937
|
71.5 ± 1.35b
|
46.9 ± 1.18b
|
11.5 ± 0.95
|
|
0.0468
|
61.8 ± 1.16b
|
31.3 ± 2.81b
|
12.0 ± 2.83
|
|
0.0234
|
41.2 ± 0.81b
|
27.4 ± 1.61b
|
9.9 ± 2.02
|
|
0.0117
|
14.7 ± 1.81b
|
20.5 ± 1.28b
|
8.8 ± 1.44
|
|
0.0058
|
10.8 ± 0.35
|
12.4 ± 1.17
|
6.3 ± 0.64
|
|
0.0029
|
9.1 ± 0.59
|
–
|
–
|
| |
IC50 = 0.044 mg/ml
|
IC50 = 0.117 mg/ml
|
IC50 = 0.280 mg/ml
|
| |
R2 = 0.983
|
R2 = 0.989
|
R2 = 0.994
|
|
Levamisol (20 mg/ml)
|
99.8 ± 0.21b
|
99.8 ± 0.21b
|
99.8 ± 0.21b
|
|
DMSO (1%)
|
9.3 ± 2.16
|
7.8 ± 0.72
|
7.5 ± 3.17
|
- Abbreviations:C50, inhibitory concentration 50%; R2, nonlinear correlation
- aNo statistically significant difference between positive control and treatments
- bSignificant difference between positive control or treatments with negative control (ANOVA, followed by Tukey test; P < 0.05)
