Fig. 3
From: Physiological and immunological responses to Culicoides sonorensis blood-feeding: a murine model
Dermal infiltration of CD16/32+ leukocytes in response to Culicoides sonorensis midge feeding. Immunofluorescent staining of micro-thin sections of BALB/c mouse abdominal skin with an anti-CD16/32 FcγIII/II receptor antibody shows infiltrating CD16+/32+ cells in hypodermal spaces beneath midge-exposed epidermis (ep), associated with edema (ed) and fluid filled vesicles (v). Boxed areas in a, c, e and g (100×; scale-bars: 100 μm) reflect regions of higher magnification shown in b, d, f and h (200×; scale-bars: 50 μm). Time points shown are 1-day post-feeding (dpf) (a, b); 2 dpf (c, d); 3 dpf (e, f); compared to naïve control mice with not exposed to midge feeding (g, h)