Table 1 Gene Ontology and metabolic enriched pathways of the 99-percentile common most highly expressed gene products

Category

GO ID

Term

FDR

P-value

Test^a

Ref^b

Cell component

GO:0005840

Ribosome

7.98E-09

3.56E-12

15

172

GO:0022627

Cytosolic small ribosomal subunit

1.77E-04

5.93E-07

3

3

GO:0000314

Organellar small ribosomal subunit

4.84E-02

7.12E-04

2

5

Molecular function

GO:0003735

Structural constituent of ribosome

1.89E-08

1.26E-11

14

154

GO:0015114

Phosphate ion transmembrane transporter activity

9.55E-03

7.24E-05

2

2

GO:0005315

Inorganic phosphate transmembrane transporter activity

9.55E-03

7.24E-05

2

2

GO:0003924

GTPase activity

1.35E-02

1.11E-04

5

57

GO:0004478

Methionine adenosyltransferase activity

2.11E-02

2.16E-04

2

3

GO:0019843

rRNA binding

2.87E-02

3.07E-04

3

16

GO:0005515

Protein binding

2.92E-02

3.19E-04

10

325

GO:0005200

Structural constituent of cytoskeleton

3.33E-02

3.71E-04

3

17

GO:0015224

Biopterin transporter activity

3.33E-02

4.30E-04

2

4

Biological processes

GO:0006412

Translation

9.19E-07

1.43E-09

15

261

GO:0006817

Phosphate ion transport

9.55E-03

7.24E-05

2

2

GO:0000028

Ribosomal small subunit assembly

9.55E-03

7.24E-05

2

2

GO:0006915

Apoptotic process

1.67E-02

1.60E-04

3

13

GO:0006556

S-adenosylmethionine biosynthetic process

2.11E-02

2.16E-04

2

3

GO:0015877

Biopterin transport

3.33E-02

4.30E-04

2

4

GO:0006986

Response to unfolded protein

3.33E-02

4.30E-04

2

4

GO:0051258

Protein polymerization

4.35E-02

6.11E-04

3

20

Database

Pathway ID

Pathway description

FDR

P-value

Test^a

Ref^b

KEGG

ec00270

Cysteine and methionine metabolism

1.64E-02

1.64E-02

2

74

TrypanoCyc

SAM-PWY

S-adenosyl-L-methionine biosynthesis

3.74E-04

6.24E-05

2

3

PWY-802

methionine and S-adenosylmethionine synthesis

3.74E-04

9.35E-05

2

4

PWY0-781

aspartate superpathway

5.96E-04

2.24E-04

2

7

PWY1V8-2

Methionine salvage cycle

8.17E-04

4.09E-04

2

10

PWY1V8-6

Trypanothine biosynthesis and peroxide metabolism

1.04E-03

6.48E-04

2

13

METHIONINE-DEG1-PWY

methionine degradation I (to homocysteine)

1.05E-02

7.84E-03

2

50

PWY0-381-1

glycerol degradation I

1.27E-02

1.11E-02

1

3