Fig. 4
From: Host-parasite interaction: changes in human placental gene expression induced by Trypanosoma cruzi
Enrichment map of gene sets of biological processes pathways. HPCVE were incubated for 2 and 24 h with 105 or 106 T. cruzi trypomastigotes/ml. Genes with fold changes ≥ 2 (P ≤ 0.05) were considered for the analysis. Gene set analysis (GSEA) was performed based in pathways from GO biological processes. Nodes correspond to gene sets and connecting lines to overlapping member genes between nodes. Divided circles represent predicted pathways, each segment of the circle represents a different experimental group according to attached legend and colors depict upregulated (red) or downregulated (blue) genes. Clusters grouped by biological function were manually labeled