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Table 4 Enteromyxum leei induces a shift towards a TH1 environment in the intestine of gilthead sea bream

From: Hints on T cell responses in a fish-parasite model: Enteromyxum leei induces differential expression of T cell signature molecules depending on the organ and the infection status

Organ Head kidney Spleen Anterior intestine Posterior intestine
Group CTRL RCPT CTRL RCPT CTRL RCPT CTRL RCPT
tbet / gata3 ratio 3.90 ± 0.43a 5.10 ± 0.73 2.54 ± 0.40a 2.65 ± 0.23 0.53 ± 0.09b 1.45 ± 0.13* 0.94 ± 0.14b 1.13 ± 0.10
ifnγ / il4 / 13a ratio 6.72 ± 3.08a 4.16 ± 1.62 18.35 ± 5.14a 9.79 ± 2.45 1.06 ± 0.33b 2.63 ± 0.52* 0.59 ± 0.10 b 1.74 ± 0.38*
  1. The TH1 / TH2 balance was assessed as the ratio of tbet / gata3 and ifnγ / il4 / 13a expression values for each individual fish in the study. Data are shown as mean ± SEM for n = 10 fish. Asterisks (*) indicate significant differences between E. leei-exposed (RCPT) and control (CTRL) groups within each organ (t-test, P < 0.05). Different superscript letters indicate significant differences in the CTRL groups among all organs within each calculated ratio (ANOVA, P < 0.05)