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Fig. 5 | Parasites & Vectors

Fig. 5

From: Hematobin is a novel immunomodulatory protein from the saliva of the horn fly Haematobia irritans that inhibits the inflammatory response in murine macrophages

Fig. 5

HTB downmodulates CD40 expression by activated macrophages and does not induce cell death. Macrophages were pre-incubated overnight with HTB (1000 nM) and stimulated with LPS plus IFN-γ (10 ng/ml of each). Flow cytometry was employed to evaluate the CD40+ events in F4/80+ gated cells after 24 h (a); and annexin V+ events in F4/80+ gated cells after 2 h and 18 h (b). The data are expressed as the percentage of positive events for each marker

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Parasites & Vectors

ISSN: 1756-3305

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