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Table 1 DNA sequence polymorphism and test of neutrality for Myanmar PfMSP-142

From: Genetic diversity of merozoite surface protein-1 C-terminal 42 kDa of Plasmodium falciparum (PfMSP-142) may be greater than previously known in global isolates

Allele type/ Fragment

Segregating sites

Singleton variable sites

Parsimony informative sites

Total no. of mutations

K

H

Hd ± SD

π ± SD

dN-dS

Tajima’s D (P)

Fu & Li’s D (P)

Fu & Li’s F (P)

MAD20

 Block 15

2

0

2

2

0.604

4

0.536 ± 0.066

0.00313 ± 0.00049

 

0.50117

(P>0.10)

0.78020

(P>0.10)

0.81005

(P>0.10)

 Block 16

10

6

4

10

1.880

8

0.769 ± 0.043

0.00272 ± 0.00035

 

-0.65200

(P>0.10)

-2.01692

(P>0.10)

-1.86022

(P>0.10)

 Block 17

7

2

5

7

1.817

6

0.632 ± 0.072

0.00533 ± 0.00062

 

0.23510

(P>0.10)

-0.20232

(P>0.10)

-0.07845

(P>0.10)

 Full

19

8

11

19

4.300

21

0.902 ± 0.040

0.00351 ± 0.00033

0.0028

-0.18385

(P>0.10)

-1.6252

(P>0.10)

-0.99150

(P>0.10)

K1

 Block 15

1

0

1

1

0.471

2

0.471 ± 0.082

0.00214 ± 0.00037

 

1.16615

(P>1.10)

0.66689

(P>0.10)

0.91015

(P>0.10)

 Block 16

4

2

2

4

0.641

4

0.477 ± 0.134

0.00102 ± 0.00037

 

-1.34736

(P>0.10)

-0.70114

(P>0.10)

-1.00781

(P>0.10)

 Block 17

2

1

1

2

0.320

3

0.307 ± 0.132

0.00093 ± 0.00042

 

-1.09629

(P>0.10)

-0.55220

(P>0.10)

-0.79776

(P>0.10)

 Full

7

3

4

7

1.431

6

0.765 ± 0.080

0.00120 ± 0.00026

−0.0012

-1.00674

(P>0.10)

-0.51291

(P>0.10)

-0.74949

(P>0.10)

RO33

 Block 15

1

1

0

1

0.143

2

0.143 ± 0.119

0.00074 ± 0.00062

 

-1.15524

(P>0.10)

-1.39749

(P>0.10)

-1.52388

(P>0.10)

 Block 16

4

3

1

4

0.791

4

0.571 ± 0.132

0.00115 ± 0.00039

 

-1.22200

(P>0.10)

-1.41428

(P>0.10)

-1.55406

(P>0.10)

 Block 17

4

4

8

4

0.571

3

0.275 ± 0.148

0.00168 ± 0.00108

 

-1.79759

(P>0.10)

-2.27380

(P>0.10)

-2.44883

(P>0.10)

 Full

9

8

1

9

1.506

6

0.736 ± 0.109

0.00123 ± 0.00041

0.0015

-1.79616

(P<0.05)

-2.26934

(P<0.05)

-2.45049

(P<0.05)

  1. Abbreviations: K average number of pairwise nucleotide differences, H number of haplotypes, Hd haplotype diversity, π observed average pairwise nucleotide diversity, dN rate of non-synonymous mutations, dS rate of synonymous mutations