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Table 3 Top detoxification genes upregulated in RDDT-S, Rperm-S and C-S

From: Molecular basis of permethrin and DDT resistance in an Anopheles funestus population from Benin

Probe name Systematic name RDDT-S fold change (FC) Rperm-S fold change (FC) C-S fold change (FC) Ortholog in An. gambiae Description
CUST_500_PI426302897 Afun000500 36.2 38.1 41.4 na Glycogenin
CUST_9227_PI426302897 Afun009227 22.2 23.3 25.6 AGAP008141-PA Argininosuccinate lyase
CUST_45_PI426302897 Afun000045 (GSTE2) 13.3 10.9 15.2 AGAP009194-PA Glutathione-S-transferase
CUST_4223_PI426302897 Afun004223 12.8 10.6 9.4 AGAP008358-PA Cytochrome p450 4d1
CUST_9697_PI426302897 Afun009697 11.6 4.8 6.8 AGAP006364-PA Abc transporter
CUST_1822_PI406199769 combined_c920 11.5 11.1 11.4   Glutathione-S-transferase
CUST_3220_PI426302897 Afun003220 10.8 5.7 7.0 AGAP002867-PA Cytochrome p450
CUST_9492_PI426302897 Afun009492 7.9 16.4 3.7 AGAP001722-PA Carboxylesterase
CUST_8615_PI426302897 Afun008615 (CYP6AA1 ) 5.1 5.2 3.8 AGAP002862-PA Cytochrome p450
CUST_9_PI426302915 CYP6M4.seq 4.9 4.8 3.5   Cytochrome p450
CUST_8445_PI426302897 Afun008445 (GSTE4) 4.3 3.9 4.7 AGAP009193-PA Glutathione-S-transferase
CUST_6930_PI426302897 Afun006930 (CYP6M7) 4.0 34.6 28.9 AGAP008212-PA Cytochrome p450 6a8
CUST_25_PI426302915 CYP6Y2_rvcpl.seq 3.4 3.7 3.8   Cytochrome p450
CUST_20_PI426302915 CYP6S1.seq 3.0 2.3 2.2   Cytochrome p450
CUST_8909_PI426302897 Afun008909 (CYP4K2) 2.8 2.4 2.0 AGAP002416-PA Cytochrome p450
CUST_1392_PI426302897 Afun001392 2.5 3.3 3.4 na Glycine dehydrogenase
CUST_13218_PI426302897 Afun013218 (CYP315A1) 2.3 2.9 2.6 AGAP000284-PA Cytochrome p450
CUST_7499_PI426302897 Afun007499 (GSTD1) 2.2 2.0 2.6 AGAP004164-PA Glutathione transferase
CUST_11037_PI426302897 Afun011037 6.5 3.7   AGAP003581-PA Alcohol dehydrogenase
CUST_12343_PI426302897 Afun012343 (CYP4H18 ) 5.2 5.0   AGAP008358-PA Cytochrome p450 4d1
CUST_10836_PI426302897 Afun010836 4.3 4.8   AGAP006228-PA Esterase b1
CUST_7769_PI426302897 Afun007769 (CYP9K1 ) 3.0 2.2   AGAP000818-PA Cytochrome p450 cyp9k1
CUST_7469_PI426302897 Afun007469 (CYP9J3) 2.0 2.1   AGAP012296-PA Cytochrome p450
CUST_12461_PI426302897 Afun012461   8.4 10.9 AGAP000288-PA Alcohol dehydrogenase
CUST_3489_PI406199769 combined_c1762   2.2 2.2   Abc transporter
CUST_8026_PI426302897 Afun008026   2.1 2.2 AGAP003578-PA Aldehyde dehydrogenase
CUST_1458_PI406199769 combined_c738 10.4   15.9   Short-chain dehydrogenase
CUST_4043_PI406199772 CD577345.1 4.4   3.7   Cuticle protein
CUST_15331_PI426302897 Afun015331 (CYP307A1) 3.4   2.2 AGAP001039-PB Cytochrome p450 307a1
CUST_25_PI406199775 CYP6P9a 2.8   2.3   Cytochrome p450
CUST_13481_PI426302897 Afun013481 (GSTE1 ) 2.5   2.7 AGAP009195-PA Glutathione-S-transferase gst
CUST_4048_PI406199772 CD577343.1   5.3    Cuticle protein
CUST_11042_PI426302897 Afun011042   3.9   AGAP003321-PA Glycine dehydrogenase
CUST_1_PI426302915 CYP6M1a.seq   2.9    Cytochrome p450
CUST_9335_PI426302897 Afun009335 (CYP6AG1)   2.4   AGAP003343-PA Cytochrome p450
CUST_13475_PI426302897 Afun013475 3.2    AGAP003582-PA Alcohol dehydrogenase
CUST_5448_PI426302897 Afun005448 (CYP302A1) 2.6    AGAP005992-PA Cytochrome p450
CUST_4047_PI406199772 CD577343.1 2.4     Cuticle protein
CUST_8823_PI426302897 Afun008823 (CYP4D15 ) 2.4    AGAP002418-PA Cytochrome p450
CUST_7301_PI426302897 Afun007301 (CYP4J5) 2.2    AGAP006048-PA Cytochrome p450
CUST_208_PI406199788 gb-CYP12F3 2.1     Cytochrome p450
CUST_10630_PI426302897 Afun010630 2.1    AGAP002866-PA Cytochrome p450
CUST_7722_PI426302897 Afun007722    3.2 AGAP009850-PA Abc transporter
CUST_12261_PI426302897 Afun012261    2.8 AGAP005758-PA Carboxylesterase
CUST_4088_PI406199772 CD577323.1    2.4   Cuticle protein
CUST_493_PI426302897 Afun000493    2.1 AGAP006225-PA Aldehyde oxidase
  1. Abbreviation: na not available