Table 13 Summary of results by compound
Compound | Longevity reduction (%) | Trehalase activities | β-glucosidase activities | Quantification sugar ingested (ηl) | Anti-Leishmania | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Males | Females | Males | Females | Males | Females | Males | Females | Culture | Infection | |
Amygdalin | ne | 13 | nt | nt | nt | nt | nt | nt | ne | nt |
Esculin | 12 | 13 | ne | RBT/RBS inhibition (ivt) | ne | RBS activation (ivv) | 20.4 ± 1.9 | 13.1 ± 1.5 | ne | nt |
Mandelonitrile | 59 | 33 | nt | nt | nt | nt | nt | nt | Yes, all species tested | nt |
Esculetin | -29 | ne | GC inhibition (ivt) | RBT inhibition (ivt) | ne | RBS activation (ivt) | 19 ± 3 | 26 ± 3 | Yes, L. infantum/L. mexicana | Yes, L. mexicana |