|
Direct feeding
|
Control
|
Fluralaner
|
|---|
|
n
a
|
Deathsbn (%)
|
95% CI
|
N
a
|
Deathsbn (%)
|
95% CI
|
Efficacyc(%)
|
P-valued
|
|---|
|
Day -7
|
138
|
3 (2)
|
0–5
|
123
|
2 (2)
|
0–4
|
0
|
0.75
|
|
Day 3
|
147
|
6 (4)
|
0–7
|
151
|
151 (100)
|
nae
|
100
|
<0.0001
|
|
Day 17
|
150
|
3 (2)
|
0–4
|
146
|
143 (98)
|
96–100
|
93
|
<0.0001
|
|
Day 31
|
148
|
2 (1)
|
0–3
|
159
|
150 (95)
|
91–98
|
94
|
<0.0001
|
|
Day 45
|
141
|
13 (10)
|
5–15
|
148
|
138 (89)
|
84–93
|
75
|
<0.0001
|
|
Day 73
|
153
|
34 (22)
|
13–28
|
182
|
75 (42)
|
35–49
|
26
|
<0.08
|
- aNumber of sand flies exposed to direct-feed on dogs
- bNumber (%) of sand flies dead 24 h after direct-feeding
- cEfficacy as the percentage of phlebotomine mortality due to the insecticide effect calculated according to adapted Henderson-Tilton’s formula
- d(Two-sided) probability values associated with the comparison on sand fly mortality between control and fluralaner using Fisher’s exact test
- eAll samples showed 100% death so there is no 95% CI
