Table 1 Observed efficacy and induced mortality of fluralaner against sand flies 24 hours after exposure on dogs
Direct feeding | Control | Fluralaner | ||||||
|---|---|---|---|---|---|---|---|---|
n a | Deathsbn (%) | 95% CI | N a | Deathsbn (%) | 95% CI | Efficacyc(%) | P-valued | |
Day -7 | 138 | 3 (2) | 0–5 | 123 | 2 (2) | 0–4 | 0 | 0.75 |
Day 3 | 147 | 6 (4) | 0–7 | 151 | 151 (100) | nae | 100 | <0.0001 |
Day 17 | 150 | 3 (2) | 0–4 | 146 | 143 (98) | 96–100 | 93 | <0.0001 |
Day 31 | 148 | 2 (1) | 0–3 | 159 | 150 (95) | 91–98 | 94 | <0.0001 |
Day 45 | 141 | 13 (10) | 5–15 | 148 | 138 (89) | 84–93 | 75 | <0.0001 |
Day 73 | 153 | 34 (22) | 13–28 | 182 | 75 (42) | 35–49 | 26 | <0.08 |