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Table 2 Anopheles sundaicus (s.l.) populations with discriminating activities of GST, EST and MO and insensitive target site AChE

From: Susceptibility to common insecticides and detoxifying enzyme activities in Anopheles sundaicus (sensu lato) after cessation of indoor residual spraying of insecticides in the Jaffna Peninsula and its surroundings in northern Sri Lanka

District Enzyme activity profiles AChE (%)a GSTb ESTc MOd
< 30 [SS] 30–70 [RS] > 70 [RR]
Jaffna district % population(a) in different categories and (b-d) with elevated activities 50 35 15 30 0 0
Mean activity ± SE     0.38 ±0.02 0.04 ±0.002 0.03 ±0.001
Kilinochchi district % population(a) in different categories and (b-d) with elevated activities 78 17 5 100 0 0
Mean activity ± SE     1.85 ±0.08 0.06 ±0.004 0.003 ±0.001
Pooled data for both districts % population (a) in different categories and (b-d) with elevated activities 68 23 9 69 0 0
Mean activity ± SE     1.14 ±0.09 0.06 ±0.004 0.02 ±0.002
  1. Abbreviation: SE standard error of the mean
  2. aPercent remaining activity of AChEs in individual mosquitoes after Propoxure inhibition in homozygous (SS) sensitive, heterozygous (RS) and homozygous (RR) insensitive populations [24]
  3. bPercentage of population having glutathione S-transferase (GST) discriminant specific activity above 0.40 μmol/mg/min and mean specific activities
  4. cPercentage of population having esterase (EST) discriminant specific activity above 0.25 μmol/mg/min and mean specific activities
  5. dPercentage of population having monooxygenase (MO) levels above the discriminant activity of 0.35 units per mg protein of cytochrome P450 and mean specific activities [18, 23]