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Fig. 1 | Parasites & Vectors

Fig. 1

From: Identification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg production

Fig. 1

HDAC inhibitors collection screening. a For each microplate the quality of the assay was carried out by the Z’ calculation. Positive controls wells (n = 16) were treated with 10 μM gambogic acid whereas negative wells (n = 16) were treated with vehicle (DMSO). All plates were found to be above the 0.5 quality threshold. b The percentage of ATP reduction (death of schistosomula) for all compounds (tested at 10 μM) normalized against DMSO and gambogic acid

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Parasites & Vectors

ISSN: 1756-3305

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