Risk factors for lymphatic filariasis in two villages of the Democratic Republic of the Congo

Parasites & Vectors

Table 5 Multivariable logistic regression analysis of risk factors for filarial antigenaemia and microfilaraemia in the total population

Variable	Category	Antigenaemia model^a				Microfilaraemia model^a
		Full model		Final model		Full model		Final model
		Adj OR (95% CI)^b	P	Adj OR (95% CI)^c	P	Adj OR (95% CI)^b	P	Adj OR (95% CI)^d	P
Previous AH treatment	Levamisole (n = 117)	0.41 (0.22–0.76)	0.005	0.40 (0.21–0.76)	0.005	0.40 (0.16–0.98)	0.046	0.41 (0.17–0.99)	0.048
(ref: no)	Mebendazole (n = 53)	0.75 (0.35–1.61)	0.460	0.77 (0.35–1.69)	0.509	0.52 (0.17–1.52)	0.237	0.56 (0.19–1.64)	0.291
	Albendazole (n = 52)	0.79 (0.37–1.65)	0.525	0.73 (0.34–1.55)	0.414	0.36 (0.10–1.29)	0.115	0.35 (0.10–1.24)	0.104
LR test random effect			0.065		0.005		0.252		0.197

^aAs only one individual had taken pyrantel, the models were performed on 819 individuals (the subject having taken pyrantel was considered as missing data)
^bAdjusted on age, sex, latrine, bednets, village, occasional overnight stay in the bush, agricultural activity, fishing, distance to the Nsitim and Kwilu rivers, population density and number of household members
^cAdjusted on age, sex, occasional overnight stay in the bush, bednets, distance to the Nsitim and Kwilu rivers, and agricultural activity
^dAdjusted on age, sex, occasional overnight stay in the bush, and distance to the Nsitim River
Abbreviations: Adj OR, adjusted odds ratio; AH, anthelmintic drug; CI, confidence interval; LR, likelihood ratio

ISSN: 1756-3305