Fig. 1
From: Identification and characterization of Pv50, a novel Plasmodium vivax merozoite surface protein
Primary structure and sequence characterization of Pv50. a Schematic diagram of Pv50. The Pv50 protein contains 460 amino acids, with a calculated molecular mass of 50.4 kDa. Indicated are the signal peptide (amino acid (aa) positions 1–19) and lipid attachment site (aa, 1–25). Truncated Pv50 (20–460 aa) was constructed for expression. b Phylogenetic tree showing the relationships among protein sequences of P. cynomolgi, P. inui, P. fragile, P. coatneyi, P. vivax, P. knowlesi and P. malariae 50 genes. The position of P. vivax pv50 is indicated with a red arrow. c Sliding window plot showing the nucleotide diversity of the pv50 in 64 worldwide isolate sequences with window size of 25 and a step size of 5