Fig. 1
Transcriptional profiling of sheep PBMCs stimulated by H. contortus soluble extract (HcAg). Sheep PBMCs were stimulated for 6 h with native HcAg (Native, 50 μg/ml), proteinase K-treated HcAg (PK, 50 μg/ml), periodate-treated HcAg (PI, 50 μg/ml) or polymyxin B-treated HcAg (PMB, 50 μg/ml), and transcriptional profiling was determined by RNA-seq. a Venn diagram showing overlap between differentially expressed genes of sheep PBMCs after stimulation. b Gene ontology-term analysis of differentially expressed genes. Pcorrected < 0.001