Fig. 3

DW-3-15 inhibited worm pairing and egg output in vitro. Adult couples were incubated with the indicated concentrations of DW-3-15 and worm pairing and total egg counts assessed as described in methods. a Pairing curves of adult couples for 24 h; b total egg counts normalized to worm couples for 24 and 96 h. The negative control group was incubated with complete DMEM containing 0.1% DMSO. The control group was incubated with complete DMEM alone. Significant differences compared to the negative control group are indicated by **P < 0.01 and ***P < 0.001