Table 1 In vivo effect of DW-3-15 against S. japonicum infected mice
Group and dose (mg/kg per day)a | Worm burden (Mean ± SD) | Worm burden reduction (%) | No. of eggs × 103/g liver tissue | Egg reduction (%) | ||||
|---|---|---|---|---|---|---|---|---|
Female | Male | Total | Female | Male | Total | |||
Controlb | 24.0 ± 1.9 | 29.0 ± 2.3 | 53.0 ± 3.4 | – | – | – | 23.8 ± 5.2 | – |
DW-3-15(400) | 7.0 ± 2.0 | 12.4 ± 1.8 | 19.4 ± 1.7* | 70.8 | 57.2 | 63.4 | 3.4 ± 0.5* | 85.8 |
PZQ(400) | 0 ± 0 | 0.6 ± 0.5 | 0.6 ± 0.5* | 100.00 | 97.9 | 98.9 | 0.7 ± 0.3* | 97.0 |