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Table 5 Pathway analysis results obtained with MetaboAnalyst

From: Deciphering the metabolic perturbation in hepatic alveolar echinococcosis: a 1H NMR-based metabolomics study

Key Pathway name Totala Hitb Impactc − log(P)
1 Alanine, aspartate and glutamate metabolism 24 2 0.38 10.94
2 Aminoacyl-tRNA biosynthesis 75 9 0.17 21.18
3 Arginine and proline metabolism 77 4 0.07 8.17
4 d-glutamine and d-glutamate metabolism 11 2 0.14 10.94
5 Glycine, serine and threonine metabolism 48 3 0.16 12.44
6 Glyoxylate and dicarboxylate metabolism 50 2 0.15 5.08
7 Lysine biosynthesis 32 1 0.10 9.94
8 Lysine degradation 47 1 0.15 9.94
9 Methane metabolism 34 2 0.16 7.15
10 Phenylalanine metabolism 45 3 0.12 11.72
11 Tyrosine metabolism 76 2 0.11 7.54
12 Valine, leucine and isoleucine biosynthesis 27 3 0.04 17.37
13 Valine, leucine and isoleucine degradation 40 3 0.02 17.37
  1. aThe total number of compounds in the pathway
  2. bThe actual matched number from the user uploaded data
  3. cThe pathway impact value calculated from pathway topology analysis
  4. dThe original P-value calculated from the logarithm analysis