Fig. 3

Transcription profile analysis of significantly differentially expressed genes. a Venn diagram showing the total number of expressed genes in each group in the large circles, and the number of genes expressed in both groups are shown in overlapping portion of the circles. b Volcano map showing significantly differentially expressed genes represented by red dots (upregulated) and green dots (downregulated). Genes that were not significantly differentially expressed are represented by blue dots. Abscissas indicate fold changes in gene expression between samples. Ordinates represent the statistical significance of the difference in gene expression. c Hierarchical clustering map of DEGs showing the overall FPKM. log10 (FPKM+1) values are scaled and clustered, with red representing upregulated genes and blue representing downregulated genes. Colors from red to blue indicate log10 (FPKM+1) values from largest to smallest. Abbreviations: C, worms from primary-infected water buffaloes; T, re-infected water buffaloes