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Table 1 KEGG enrichment analysis of the up- and downregulated genes in the La-SbIII-R line

From: Transcriptional responses of Leishmania (Leishmania) amazonensis in the presence of trivalent sodium stibogluconate

Pathway ID Map name Genes
Upregulated genes
 ec00240 Pyrimidine metabolism LmxM.13.1630, LmxM.18.1580, LmxM.21.1210, LmxM.23.0680, LmxM.28.0890, LmxM.28.1420, LmxM.28.1430, LmxM.33.0010, LmxM.34.1790
Downregulated genes
 ec00130 Ubiquinone and other terpenoid-quinone biosynthesis LmxM.05.1100, LmxM.34.0500, LmxM.34.0500a, LmxM.34.0520b, LmxM.34.0540, LmxM.34.0550
 ec00260 Glycine, serine and threonine metabolism LmxM.10.0090, LmxM.14.1320, LmxM.29.2090, LmxM.32.0520, LmxM.36.3800
 ec00053 Ascorbate and aldarate metabolism LmxM.10.0090, LmxM.18.0160, LmxM.26.0160, LmxM.32.0520, LmxM.33.0010, LmxM.34.0500, LmxM.34.0500a, LmxM.34.0520b, LmxM.34.0540, LmxM.34.0550
 ec00670 One carbon pool by folate LmxM.14.1320, LmxM.36.3800, LmxM.36.6390
 ec00980 Metabolism of xenobiotics by cytochrome P450 LmxM.29.2090, LmxM.32.0240
 ec00982 Drug metabolism - cytochrome P450 LmxM.29.2090, LmxM.32.0240
 ec00531 Glycosaminoglycan degradation LmxM.34.0500, LmxM.34.0500a, LmxM.34.0520b, LmxM.34.0540, LmxM.34.0550