|
Fecundity (egg output per female worm in absence of density dependence)
|
0.34 eggs/female worm/sample
|
[11, 23, 24]
|
|
Variation in egg counts within individuals
|
0.87
|
[23, 24]
|
|
Aggregation parameter for high baseline prevalence settings
|
0.24
|
[5, 25, 26]
|
|
Density dependence fecundity
|
0.0007/female worm
|
[12, 25]
|
|
Worm lifespan
|
5.7 years
|
[11, 27]
|
|
Drug efficacy
|
86%
|
[28]
|
|
Low adult burden setting: age-specific contact rates for 0–5, 5–10, 10–16, 16+ years of age
|
0.01, 1.2, 1, 0.02
|
[5, 12]
|
|
High adult burden setting: age-specific contact rates for 0–5, 5–12, 12–20, 20+ years of age
|
0.01, 0.61, 1, 0.12
|
[5, 12]
|
|
Prevalence of infection
|
Percentage of population having egg count threshold (or eggs per gram, epg) > 0
|
–
|
|
Prevalence of heavy-intensity infections
|
Percentage of population having egg count threshold ≥ 16 (epg ≥ 400 divided by 24 to convert to egg count)
|
[29]
|
|
Human demography
|
Based on Uganda’s demographic profile
|
[30, 31]
|
