Table 1 Parameter values used for Schistosoma mansoni

Fecundity (egg output per female worm in absence of density dependence)

0.34 eggs/female worm/sample

[11, 23, 24]

Variation in egg counts within individuals

0.87

[23, 24]

Aggregation parameter for high baseline prevalence settings

0.24

[5, 25, 26]

Density dependence fecundity

0.0007/female worm

[12, 25]

Worm lifespan

5.7 years

[11, 27]

Drug efficacy

86%

[28]

Low adult burden setting: age-specific contact rates for 0–5, 5–10, 10–16, 16+ years of age

0.01, 1.2, 1, 0.02

[5, 12]

High adult burden setting: age-specific contact rates for 0–5, 5–12, 12–20, 20+ years of age

0.01, 0.61, 1, 0.12

[5, 12]

Prevalence of infection

Percentage of population having egg count threshold (or eggs per gram, epg) > 0

–

Prevalence of heavy-intensity infections

Percentage of population having egg count threshold ≥ 16 (epg ≥ 400 divided by 24 to convert to egg count)

[29]

Human demography

Based on Uganda’s demographic profile

[30, 31]