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Table 5 Geometric mean microfilaria counts (number of microfilariae per ml)

From: Safety of an extended-release injectable moxidectin suspension formulation (ProHeart® 12) in dogs

Study day

Control (n = 8)

1.50 mg/kg moxidectin (n = 7)

% Reductiona

Day -70

0

0

 

Day -49

6.4

4.8

 

Day -35

55.5

113.8

 

Day -21

730.6

1743.4

 

Day -7

3401.1

4855.3

 

Day -2

2648.3

2446.4

 

Day 1

4228.8

5622.0

0

Day 4

4393.4

693.1

84.22

Day 8

4828.5

57.4

98.81

Day 15

6271.6

5.6

99.91

Day 22

9269.0

4.6

99.95

Day 29

7413.1

2.5

99.97

Day 43

5186.0

4.2

99.92

  1. aPercent reduction is compared to controls at the same time point