Immediate and persistent efficacy of sarolaner (Simparica™) against Haemaphysalis elliptica on dogs

Parasites & Vectors

Table 2 Arithmetic and geometric mean tick^a counts and efficacy of the IVP^b

Day	Placebo^c		Sarolaner		% efficacy
Day	Mean^d	Range	Mean	Range	% efficacy
2	26.8 (27.9)	18–49	0	0–0	100
7	31.9 (32.5)	22–40	0	0–0	100
14	36.8 (37.4)	30–48	0	0–0	100
21	26.2 (27.3)	14–35	0	0–0	100
28	30.6 (31.4)	19–41	0	0–0	100
35	39.2 (39.9)	26–49	0	0–0	100

^aLaboratory tick strain used was obtained from Clinvet, Bloemfontein, Free State, South Africa
^bCommercial chewable tablet formulation (Simparica™) containing sarolaner as active ingredient
^cChewable tablet with vehicle compounds only
^dMean values indicated as: geometric (arithmetic)
Note: Difference in mean tick count was significant (ANOVA, F_{(1, 15)} = 69.41, P < 0.0001) in all instances) for all assessment days

ISSN: 1756-3305