Table 1 Analysis variables weighted to the district and stratified by the outcome of residing in a hotspot versus residing in a district that was not a statistically significant hotspot identified using the Getis-Ord Gi*(d) statistic (n = 152), Amhara, Ethiopia, 2011–2016

Individual

 Trachomatous inflammation-follicular (%)

25.08 ± 16.19

23.08 ± 14.53

48.54 ± 16.79

1.13 (1.07–1.20)

 Children with clean faces (%)

80.58 ± 11.13

81.63 ± 10.31

68.30 ± 13.39

0.91 (0.86–0.96)

Household

 Access to a latrine

52.22 ± 19.95

53.04 ± 20.08

42.60 ± 16.24

0.97 (0.95–1.00)

 Access to a water source within 30 minutes (%)

61.58 ± 20.73

63.48 ± 19.52

39.34 ± 22.43

0.95 (0.92–0.98)

 Access to an improved water source (%)

55.07 ± 23.35

56.70 ± 22.55

36.10 ± 25.18

0.96 (0.94–0.99)

 Crowding (> 6 persons living in the home) (%)

38.22 ± 9.54

37.88 ± 9.49

42.19 ± 9.70

1.05 (0.99–1.12)

 Mean number of household items owned

1.48 ± 0.76

1.56 ± 0.74

0.52 ± 0.32

0.01 (0.00–0.11)

 Any reported formal education (%)

41.03 ± 16.99

40.73 ± 16.49

44.51 ± 22.69

1.01 (0.98–1.05)

Village

 Health facility (%)

22.53 ± 17.19

24.32 ± 16.24

15.70 ± 23.37

0.97 (0.92–1.01)

 Paved road

39.64 ± 24.19

40.78 ± 24.18

20.26 ± 14.99

0.94 (0.89–0.99)

District

 Previous rounds of MDA

6.59 ± 1.64

6.63 ± 1.68

6.25 ± 1.22

0.86 (0.59–1.26)

Climate variables

 Average annual precipitation (mm)

1135.00 ± 278.37

1135.00 ± 278.37

809.50 ± 94.27

0.98 (0.97–0.99)

 Average annual temperature (°C)

18.41 ± 3.05

18.41 ± 3.05

19.78 ± 2.25

1.16 (0.97–1.38)

 Altitude (m)

2057.91 ± 477.36

2057.91 ± 477.36

1951.42 ± 313.98

1.00 (1.00–1.00)