Skip to main content

Advertisement

Table 3 Number of samples (and percentages) found to be positive for the three different peptide serology markers

From: Assessment of multiplex Onchocerca volvulus peptide ELISA in non-endemic tropical regions

Sample setNumber (%) of plasma samples above “spot intensity cut-off” for peptide
OvMP-1OvMP-23OvNMP-483-peptide positives
Known onchocerciasis status
 Nodule positive (Ghana, n = 77)76 (98.7)75 (97.4)74 (96.1)72 (93.5)
 B. malayi (Indonesia, n = 19)18 (94.7)8 (42.1)3 (15.8)1 (5.3)
 W. bancrofti (Sri Lanka, n = 8; Tahiti, n = 2)2 (20.0)2 (20.0)2 (20.0)1 (10.0)
 Healthy controls (Belgium, n = 84)0 (0)4 (4.8)4 (4.8)0 (0)
 South America (n=89)1 (1.1)10 (11.2)7 (7.9)0 (0)
Unknown onchocerciasis status
 Kenya, Kisumu (n = 98)86 (87.8)55 (56.1)45 (45.9)30 (30.6)
 Kenya, Siaya (n = 98)83 (84.7)66 (67.3)69 (70.4)57 (58.2)
 STH/S. mansoni (Ethiopia, n = 24)3 (12.5)5 (20.8)2 (8.3)0 (0)
 Endemic controls (Ghana, n = 48)46 (95.8)46 (95.8)43 (89.6)40 (83.3)