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Table 4 Single nucleotide polymorphism frequencies for A. caninum isolates at the three different codons associated with resistance to benzimidazoles

From: Multiple drug resistance in the canine hookworm Ancylostoma caninum: an emerging threat?

Isolate/Patient

BZ phenotype (S/R)

Sample sequenced

F167Y

Freq (%)

E198A

Freq (%)

F200Y

Freq (%)

ETCR

S

250 eggs

0

0

0

ETCR

S

300 L3

8.8

0

0

Barrow

S

250 L3

1.2

0

0

Worthy

R

L3

92.2

0

0

Worthy 1.1F

R

300L3

87.6

0

0

Worthy 2.1F

R

100 L3

94.5

0

0

Tara

R

375 eggs

12.7

0

0

Tara 1.1F

R

250 L3

50.9

0

0

Lacy

R

Single adult

47.4

0

0

Lacy

R

Single adult

52.9

0

0

Lacy

R

Single adult

46.0

0

0

Lacy

R

Eggs

99.7

0

0

Fame Taker

R

350 L3

90.7

0

0

Dolores (Worthy house companion)

R

300 L3

88.9

0

0

  1. Abbreviations: BZ, benzimidazoles; Freq, frequency; L3, third-stage larvae; S/R, susceptible/resistant