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Table 4 Single nucleotide polymorphism frequencies for A. caninum isolates at the three different codons associated with resistance to benzimidazoles

From: Multiple drug resistance in the canine hookworm Ancylostoma caninum: an emerging threat?

Isolate/Patient BZ phenotype (S/R) Sample sequenced F167Y
Freq (%)
E198A
Freq (%)
F200Y
Freq (%)
ETCR S 250 eggs 0 0 0
ETCR S 300 L3 8.8 0 0
Barrow S 250 L3 1.2 0 0
Worthy R L3 92.2 0 0
Worthy 1.1F R 300L3 87.6 0 0
Worthy 2.1F R 100 L3 94.5 0 0
Tara R 375 eggs 12.7 0 0
Tara 1.1F R 250 L3 50.9 0 0
Lacy R Single adult 47.4 0 0
Lacy R Single adult 52.9 0 0
Lacy R Single adult 46.0 0 0
Lacy R Eggs 99.7 0 0
Fame Taker R 350 L3 90.7 0 0
Dolores (Worthy house companion) R 300 L3 88.9 0 0
  1. Abbreviations: BZ, benzimidazoles; Freq, frequency; L3, third-stage larvae; S/R, susceptible/resistant