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Table 3 Summary of adult flea counts and percent efficacy

From: Efficacy of lotilaner (Credelio™) against the adult cat flea, Ctenocephalides felis and flea eggs following oral administration to dogs

Day

No. of dogs flea-free (%)

Arithmetic mean (% Efficacy)

Geometric mean (% Efficacy)

Comparison

Placebo control

(n = 10)

Lotilaner

(n = 10)

Placebo control

(n = 10)

Lotilaner

(n = 10)

Placebo control

(n = 10)

Lotilaner

(n = 10)

1

0

10 (100)

91.4

0 (100)

91.2

0 (100)

t(9) = 203.12, P < 0.0001a

Z = 4.04, P < 0.0001a

7

0

10 (100)

92.6

0 (100)

92.1

0 (100)

t(9) = 123.10, P < 0.0001a

Z = 4.07, P < 0.0001a

14

0

10 (100)

92.9

0 (100)

92.5

0 (100)

t(9) = 147.43, P < 0.0001a

Z = 4.05, P < 0.0001a

21

0

10 (100)

93.1

0 (100)

92.8

0 (100)

t(9) = 167.53, P < 0.0001a

Z = 4.07, P < 0.0001a

30

0

10 (100)

87.8

0 (100)

87.5

0 (100)

t(9) = 154.22, P < 0.0001a

Z = 4.04, P < 0.0001a

  1. Note: Comparison results of both the parametric and non-parametric tests are presented
  2. aValues significantly decreased in comparison to the control group