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Table 3 Summary of adult flea counts and percent efficacy

From: Efficacy of lotilaner (Credelio™) against the adult cat flea, Ctenocephalides felis and flea eggs following oral administration to dogs

DayNo. of dogs flea-free (%)Arithmetic mean (% Efficacy)Geometric mean (% Efficacy)Comparison
Placebo control
(n = 10)
Lotilaner
(n = 10)
Placebo control
(n = 10)
Lotilaner
(n = 10)
Placebo control
(n = 10)
Lotilaner
(n = 10)
1010 (100)91.40 (100)91.20 (100)t(9) = 203.12, P < 0.0001a
Z = 4.04, P < 0.0001a
7010 (100)92.60 (100)92.10 (100)t(9) = 123.10, P < 0.0001a
Z = 4.07, P < 0.0001a
14010 (100)92.90 (100)92.50 (100)t(9) = 147.43, P < 0.0001a
Z = 4.05, P < 0.0001a
21010 (100)93.10 (100)92.80 (100)t(9) = 167.53, P < 0.0001a
Z = 4.07, P < 0.0001a
30010 (100)87.80 (100)87.50 (100)t(9) = 154.22, P < 0.0001a
Z = 4.04, P < 0.0001a
  1. Note: Comparison results of both the parametric and non-parametric tests are presented
  2. aValues significantly decreased in comparison to the control group