Fig. 4

Specific antibodies against borrelia organisms in C3H/HeOuJ mice serum. Specific antibodies against Bp (a) or Bbss (b) were induced in C3H/HeOuJ mice. a Both groups of mice, inoculated intradermally or intravenously with Bp, showed rising antibody levels until day 21 pi, followed by a slight decrease and a repeated increase until day 49/50 pi. Data for individual serum samples from single animals are represented for days 49/50 pi (bar symbols). b Mice inoculated intradermally with Bbss showed increasing levels of specific antibodies against Bbss. Data for individual serum samples from single animals are represented for days 49/50 pi (bar symbols). In contrast, specific antibodies against Bbss were not detected when mice received Bbssvia strict intravenous injection