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Fig. 7 | Parasites & Vectors

Fig. 7

From: Xiaochaihu decorction relieves liver fibrosis caused by Schistosoma japonicum infection via the HSP47/TGF-β pathway

Fig. 7

Schistosoma japonicum induced activation of macrophages was inhibited by Xiaochaihu decoction (XCH). RAW264.7 cells were treated with S. japonicum egg antigens in the presence or absence of Xiaochaihu decoction and LY2157299. a The mRNA levels of TGF-β1, CTGF, IL-13, IL-17 and IL-6 of Raw264.7 macrophages were analyzed by quantitative real-time PCR. b The levels of medium TGF-β1, CTGF, IL-13, IL-17 and IL-6 of Raw264.7 macrophages were assessed by ELISA. Abbreviations: SJ-A, S. japonicum egg antigens. **P < 0.01 compared to control, #P < 0.05 compared to infection, ##P < 0.01 compared to infection

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Parasites & Vectors

ISSN: 1756-3305

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