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Fig. 1 | Parasites & Vectors

Fig. 1

From: Activities of artesunate-based combinations and tafenoquine against Babesia bovis in vitro and Babesia microti in vivo

Fig. 1

In vitro activity of artesunate (ARS) (a), mefloquine (MEF) (b), tafenoquine (TAF) (c), primaquine (PRI) (d) and methylene blue (MB) (e) against Babesia bovis. Results are expressed as % (mean ± standard deviation) of growth at each drug concentration in relation to wells without drug (100% growth) after 4 days of culture. In the MB graph (e), wells containing uninfected red blood cells (uRBC) were run in parallel for all MB concentrations, because MB causes a background fluorescence and this background value was subtracted from the corresponding wells containing infected red blood cells (iRBC) to generate the iRBC MB drug response curve. Numbers in boxes in each graph represent the IC50 (in µm) for each given drug. Abbreviation: Conc (x-axis), concentration of the drug

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