Fig. 8

Curve of parasitemia (mean ± standard deviation) in BALB/c mice inoculated with blood of mice that had been previously infected with Babesia microti and treated with either tafenoquine (TAF) 10 mg/kg (base) or artesunate (ARS) 25 mg/kg + tafenoquine (TAF) 10 mg/kg (base). Blood (10 μl) was taken from the tail vein of each of the 5 infected and treated mice (total pooled = 50 μl) at day 30 of infection, when parasitemia was negative by microscopy but all but one mouse (group ARS + TAF) showed positive PCR for Babesia microti. The 50 μl of blood was administered intraperitoneally and parasitemia was checked by microscopy